Injectables

KYBELLA

KYBELLA is the only non-surgical treatment approved by the FDA for improving the appearance of submental fullness, often referred to as a double chin.

KYBELLA is a formulation of a naturally occurring-substance (deoxycholic acid) that targets and destroys fat cells in the area where it’s injected. Once those cells are destroyed, they can no longer store or accumulate fat.

KYBELLA leaves a smooth, contoured jawline, and re-treatment is not expected to be required.

*Individual results may varry

BOTOX®

BOTOX® is the only FDA-approved treatment for the temporary reduction of moderate to severe frown lines. Botox works by relaxing the muscles that create wrinkles, thereby lessening the appearance of frown lines, laugh lines, and “crow’s feet.” There is no recovery or downtime, and results can last from three to six months.

*Individual results may varry

BOTOX® FAQs

What is BOTOX® Cosmetic and how does it work?

BOTOX® Cosmetic (onabotulinumtoxinA) is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in people 18 to 65 years of age for a short period of time (temporary). It works by blocking the nerve impulses to the injected muscles. This reduces muscle activity that causes persistent lines to form between the brows.


Why consider BOTOX® Cosmetic?

There is no surgery or recovery time. BOTOX® Cosmetic blocks nerve impulses to the muscles in your forehead – called the “corrugator” and “procerus” muscles – reducing their movement. This decreased muscle activity helps lessen the appearance of moderate to severe frown lines between the brows for real, noticeable results.


Is BOTOX® Cosmetic right for me?

Only your healthcare professional can determine whether BOTOX® Cosmetic is right for you. However, you should not use BOTOX® Cosmetic if you are allergic to any of the ingredients in BOTOX® Cosmetic, had an allergic reaction to any other botulinum toxin product (Myobloc® [rimabotulinumtoxinB], Dysport® [abobotulinumtoxinA], or Xeomin® [incobotulinumtoxinA]), or have a skin infection at the planned injection site.


How fast will I see results?

BOTOX® Cosmetic starts to work within 24 to 48 hours. In clinical trials, a majority of people saw significant improvement at 7 days, with results continuing to improve for up to a month.¹


How long will my results last?

Visible results have been proven to last up to 4 months. Your results may vary.


Will I still be able to make facial expressions?

Although the results are visible, a treatment with BOTOX® Cosmetic (onabotulinumtoxinA) will not radically change your facial appearance or make you look as if you’ve “had work done.” The muscle activity that causes frown lines between the brows is temporarily reduced, so you can still frown or look surprised without the wrinkles and creases between your brows.


What does my health care profession need to know before my BOTOX® Cosmetic treatment?

Tell your healthcare professional about:

– All your muscle or nerve conditions (eg, amyotrophic lateral sclerosis, myasthenia gravis, or Lambert-Eaton syndrome)
– Any prescription or nonprescription medicines, vitamins, muscle relaxants, or herbal products you take, or if you have recently received an antibiotic by injection.
– All your medical conditions including previous or upcoming surgeries, weakness of forehead muscles, or any other facial abnormalities
– If you are currently pregnant or plan on becoming pregnant
– If you are currently breast-feeding or plan on breast-feeding
– If you have received any other botulinum toxin product in the past, particularly in the last 4 months

 


What are the possible side effects with BOTOX® Cosmetic treatment?

Serious and/or immediate allergic reactions have been reported. Possible side effects include itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint. Other side effects of BOTOX® Cosmetic may occur, including dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems such as double vision, blurred vision, decreased eyesight, drooping eyelids swelling of your eyelids, and dry eyes.

Dysport®

Prescription Dysport is an injection used to temporarily improve the look of your moderate to severe frown lines without changing the look of your whole face. The untreated facial muscles still work normally, allowing you to freely show facial expressions, such as smiling, in untreated areas.

Dysport is a formulation that has been shown to deliver temporary improvements in moderate to severe frown lines, even with repeat treatments. So, the effect of repeat treatment with Dysport may be comparable to your first use.

Before/After BOTOX®

*Individual results may varry

Dysport® FAQs

What is Dysport©?

Prescription Dysport® is an injection used to temporarily improve the look of your moderate to severe frown lines without changing the look of your whole face. The untreated facial muscles still work normally, allowing you to freely show facial expressions, such as smiling, in untreated areas.


How does Dysport© work?

Over time, the muscles above and between the eyebrows repeatedly contract and tighten, causing wrinkles. But, with just 1 injection into each of 5 points between and over the eyebrows, Dysport® blocks the signal from the nerve to the muscles, ultimately resulting in a reduction of muscle activity and temporarily preventing contraction of the muscles that cause frown lines.


What causes frown lines?

Frown lines are caused by a number of factors. Over time, repeated movement of the facial skin by the brow muscles forms lines between the eyebrows. Frown lines are “dynamic”—they happen because of the way a person’s face moves.


Are frown lines always related to age?

Contrary to popular belief, frown lines are not always caused by age. Age is a factor, but repeated facial movements, such as frowning or squinting can also create frown lines, which means they may develop even in younger adults.


What can you do about frown lines?

Treatment with prescription Dysport® can temporarily improve the look of your moderate to severe frown lines. Treatment generally takes just 10 to 20 minutes and results last up to 3 months.


What are the possible side effects of Dysport©?

The most common side effects are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation and nausea.

Xeomin®

Xeomin® is a prescription medication used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows in adults. Over time and as the skin ages, repeated frowning and facial expressions can cause deep and persistent lines, especially as skin loses its elasticity. When injected intramuscularly, Xeomin(R) acts on nerve endings in muscles to prevent the muscle fibers from contracting, and can temporarily reduce the lines on your forehead between your brows (frown lines). There is little or no downtime associated with this treatment, and results can last anywhere from 3 to 6 months in some patients.

Before/After

*Individual results may varry

Xeomin® FAQs

What is XEOMIN®?

XEOMIN® (incobotulinumtoxinA) for injection, for intramuscular use, is a prescription medication used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults.

XEOMIN® contains botulinum toxin type A, a naturally occurring protein purified from the bacterium Clostridium botulinum.


How does XEOMIN® work?

When you squint or frown the muscles between your brows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines.

Botulinum toxin type A – the active ingredient in XEOMIN® acts on nerve endings in muscles to prevent muscle fibers from contracting so forcefully. By reducing these contractions, XEOMIN® can temporarily reduce the lines on your forehead between your brows.


Is XEOMIN® proven?

XEOMIN® (incobotulinumtoxinA) for injection, for intramuscular use, was proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trials of 547 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of XEOMIN® and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with XEOMIN® received FDA approval for aesthetic use in 2011.


What should I tell my doctor before treatment?

Before receiving treatment with XEOMIN® (incobotulinumtoxinA) for injection, for intramuscular use, you should tell your doctor about all of your medical conditions, including whether you have a disease that affects your muscles and nerves, have allergies to any botulinum toxin product, or have experienced any side effect from any other botulinum toxin in the past.

In addition, tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Especially tell your doctor if you have received any other botulinum toxin product in the last four months or in the past. Be sure your doctor knows exactly which product(s) you received and when your received them.


What can I expect during treatment?

Visible results have been proven to last up to 4 months. Your results may vary. During treatment, which usually takes about 10-20 minutes, your doctor will inject XEOMIN® (incobotulinumtoxinA) for an injection, for intramuscular use, into the muscles in your forehead that cause frown lines between your brows. No anesthesia is required; however, your physician may use a topical anesthetic or cold pack to reduce any discomfort.


When can I expect to see results?

In clinical trials, some patients observed visible smoothing as early as 3-4 days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days. The typical duration of effect was up to 3 months in clinical trials but may last significantly longer or shorter in individual patients.


What are the possible side effects of XEOMIN®?

XEOMIN® (incobotulinumtoxinA) for injection, for intramuscular use, may cause serious side effects, including allergic reactions. Symptoms of an allergic reaction may include: itching, rash, redness, swelling, wheezing asthma symptoms, or dizziness or feeling faint. Tell your doctor or seek medical help right away if you have wheezing, experience other asthma symptoms, or if you become dizzy or faint.

Juvederm®

Juvederm® XC is the smooth gel filler that your doctor uses to instantly smooth away wrinkles around your mouth and nose. With just one treatment, you’ll get smooth and natural-looking results that last up to a year.

Juvederm® XC is manufactured using HYLACROSS(TM) technology, creating a smooth-consistency gel. It is infused with lidocaine to improve comfort during treatment. With Juvederm® XC you get the smooth results you expect, with the improved comfort you want.

*Individual results may varry

Juvederm® FAQs

What is Juvederm®?

Juvederm® is the only HA filler FDA approved* to last up to one year. Ask your physician how you can get long-lasting results with Juvederm®. Juvederm® XC injectable gel is a smooth consistency gel dermal filler that helps to instantly restore your skin’s volume and smooth away facial wrinkles and folds like your “smile lines” or “parentheses” (nasolabial folds) – the creases that run from the bottom of your nose to the corners of your mouth. JUVÉDERM XC comes in two formulations – Juvederm® Ultra XC and Juvederm® Ultra Plus XC.

*In the United States, Juvederm® is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).


What makes Juvederm® XC different from other dermal fillers?

Juvederm® XC is the ONLY hyaluronic acid (HA) filler FDA approved* to last up to 1 year after initial treatment.¹˒²˒³˒⁴ Our unique manufacturing process provides a high concentration of cross-linked hyaluronic acid for long-lasting results. It also works to create a smooth consistency gel that flows easily into the skin and provides a smooth, natural look and feel. All other hyaluronic acid dermal fillers currently on the market are made of granular consistency gels. And, Juvederm® is the first hyaluronic acid dermal filler that has demonstrated its safety and effectiveness in persons of color.

*In the United States, Juvederm® is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).
¹Most subjects acquired optimal correction at initial treatment. Some subjects required up to 2 touch-ups to achieve optimal correction.

²This includes all Juvederm® injectable gel formulations.

³Juvederm®Ultra XC Directions for Use; Juvederm® Ultra Plus XC Directions for Use.

⁴Pinsky MA, Thomas JA, Murphy DK, Walker PS; for Juvederm® vs. Zyplast® Nasolabial Fold Study Group. Juvederm® injectable gel: A multicenter, double-blind randomized study of safety and effectiveness. Aesthetic Surg J. 2008:28(1):17-23.


What is hyaluronic acid?

Hyaluronic acid is a naturally occurring substance found in all mammals that helps to hydrate and add volume to your skin. In addition to its use as an aesthetic treatment, hyaluronic acid has also been used for more than 20 years for injection into arthritic joints to aid movement as well as for eye surgeries and wound repair.


What is cross-linked hyaluronic acid?

“Uncross-linked” hyaluronic acid is its natural form is in a liquid state. “Cross-linking” is the process through which hyaluronic acid is made into a gel product that can be injected into the skin for long-lasting results.


How is Juvederm®XC injectable gel used in treatment?

Your healthcare provider eases Juvederm®XC injectable gel into the skin using a fine needle to temporarily fill in and augment the treatment area and smooth moderate to severe facial wrinkles and folds such as “smile lines” or “parentheses” (nasolabial folds) and “marionette lines” (oral commissures). Juvederm®XC temporarily adds volume to the skin and may give the appearance of a smoother surface.


Is treatment with Juvederm®XC injectable gel painful?

Injections may cause some discomfort during and after the injection. The smooth consistency gel of Juvederm® XC allows your doctor to administer it easily and smoothly. And, Juvederm® XC is injected directly into the skin using a fine needle to reduce injection discomfort. Additionally, Juvederm® XC is formulated with lidocaine for a more comfortable treatment experience.¹˒² Your doctor may choose to numb (anesthetize) the treatment area to further minimize discomfort.
¹Compared to non-lidocaine Juvederm® formulation.
²Weinkle SH, Bank DE, Boyd CM, Gold MH, Thomas JA, Murphy DK. A multi-center, double-blind, randomized controlled study of the safety and effectiveness of Juvederm® injectable gel with and without lidocaine. J Cosmet Dermatol. 2009; 8(3):205-210. Please see Juvederm®2 Ultra XC and Juvederm® Ultra Plus XC Patient Safety Information for more information.


How long does treatment usually take?

The injection process generally takes only about 15 minutes. You’ll also need to allow time to consult with your doctor prior to treatment.


Does the correction last forever?

No. Correction is temporary; therefore, touch-up injections as well as repeat injections are usually needed to maintain optimal corrections.


What are the possible side effects of Juvederm® XC injectable gel?

Most side effects are mild or moderate in nature, and their duration is short lasting (7 days or less). The most common side effects include, but are not limited to, temporary injections site reactions such as redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. As with all skin injection procedures there is a risk of infection.

Juvederm Voluma®XC

Juvederm Voluma® XC is the first and only FDA-approved filler to correct age-related volume loss in the cheek area in adults over the age of 21. It’s a nonsurgical filler that instantly provides a smooth, natural-looking appearance to the cheek area, made from modified hyaluronic acid (HA), a naturally occurring complex sugar. Juvederm Voluma® XC is specifically formulated to correct volume loss and enhance contour to the cheek area, creating a youthful appearance clinically proven to last up to 2 years with optimal treatment.

Before/After Juvederm

*Individual results may varry

Juvederm Voluma®XC FAQs

What is Juvederm Voluma® XC?

Juvederm Voluma® XC is the first and only FDA-approved filler to correct age-related volume loss in the cheek area in adults over the age of 21. It’s a nonsurgical filler that instantly provides a smooth, natural-looking appearance to the cheek area, made from modified hyaluronic acid (HA), a naturally occurring complex sugar. Juvederm Voluma® XC is specifically formulated to correct volume loss and enhance contour to the cheek area, creating a youthful appearance clinically proven to last up to 2 years with optimal treatment.


What is the difference between Juvederm® XC and Juvederm Voluma® XC?

Juvederm® XC and Juvederm Voluma® XC work on a different area of the face. Juvederm® XC smoothes out moderate to severe wrinkles and folds around the nose and mouth, like parentheses. JUVÉDERM Voluma XC, however, adds volume to the cheek area. Juvederm® XC is clinically proven to last up to 1 year with optimal correction at initial treatment, and Juvederm Voluma® XC is clinically proven to last up to 2 years with optimal treatment.


What is the difference between Juvederm Voluma® XC and other dermal fillers?

Juvederm Voluma® XC was specially designed to fill and lift the mid-face and cheeks. It uses a new advanced technology from Allergan which is called Vycross that results in a smooth gel that flows easily and consistently and which can be nicely sculpted. This special cross-linking technology not only produces the lift and fill that is unique to Voluma, but it also contributes to its long-lasting nature.


What is the treatment process?

Before the initial procedure, you will have a consultation with your healthcare provider to determine if Juvederm Voluma® XC is appropriate for you, review your expectations and desired results, review any potential side effects, as well as identify the areas to treat. Juvederm Voluma® XC is nonsurgical, and you should be able to get back to your full routine after 24 hours.


Is the treatment painful?

Juvederm Voluma® XC contains lidocaine, a numbing agent designed to minimize pain that can occur during treatment. Your doctor may also choose to numb the treatment area with a topical numbing cream to further minimize pain.


How long will my results last?

Your results will last up to two years with optimal treatment. There is evidence that hyaluronic acid fillers such as Juvederm® actually help to stimulate the production of new collagen by your own body so that longer duration of improvement may be seen. Also depending on various factors of your health, weight and body chemistry as well as the volume injected and the skill of the injector duration of correction may be shorter (or even longer) than two years.


What are possible side effects of Juvederm Voluma® XC?

Side effects are moderate (uncomfortable) and generally last 2 to 4 weeks. The most common side effects include temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration and itching.
To report a side effect, please call Allergan Product Surveillance at 1-877-345-5372

Restylane®

Restylane adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).Restylane can also add fullness and definition to lips in patients over 21 years, providing natural-looking and lasting results with just one treatment.

Restylane works immediately by adding volume to smooth away wrinkles. A clear gel formulation of hyaluronic acid, Restylane is specifically formulated to act like your body’s own hyaluronic acid. So, you can use Restylane to visibly reduce moderate to severe facial wrinkles and folds, and to add fullness to your lips.

Before/After Restylane®

*Individual results may varry

Belotero®

With Belotero Balance® Dermal Filler, you can quickly restore lost volume due to aging and plump fine lines and wrinkles with instantaneous results. Belotero Balance® Dermal Filler has a soft and smoothening effect on wrinkles and skin, and is indicated for the treatment of moderate to severe facial wrinkles and folds, such as nasolabial folds. It is designed to quickly integrate into your skin and mold to your distinct facial contours for results that may last 6 months or more. With a unique manufacturing process that offers a soft, cohesive gel, Belotero Balance® Dermal Filler is able to fill your wrinkles for results that are smooth, even, and immediate.

Before/After Belotero

*Individual results may varry

Belotero® FAQs

What is BELOTERO BALANCE® Dermal Filler?

BELOTERO BALANCE® Dermal Filler is an injectable filler that quickly integrates into your skin.¹ Once injected, it instantly smoothes the lines and wrinkles in your face.


What is the difference between BELOTERO BALANCE® Dermal Filler and others?

BELOTERO BALANCE® Dermal Filler is made of the same material (hyaluronic acid) as some other dermal fillers, BELOTERO BALANCE® Dermal Filler has unique properties that allow it to adapt within the skin for soft and even correction. ₁ The versatility of the product makes it strong enough to handle deep treatment areas such as nasolabial folds (smile lines around the mouth), yet soft enough to treat more delicate areas such as vertical lip lines (the lines that appear about the lip line).


How does it work?

BELOTERO BALANCE® Dermal Filler is made of a material called hyaluronic acid or HA. HA naturally exists as a component of your skin. By binding to water, it plumps and fills in wrinkles and folds, allowing immediate and smooth correction.


How soon can I expect results?

Instantly! Immediately upon injection when treated to full correction, BELOTERO BALANCE® Dermal Filler plumps the skin and smoothes away lines and wrinkles.


How long does it last?

Individual results may vary, but BELOTERO BALANCE® Dermal Filler may last about 6 months or more.²


How is the treatment performed?

BELOTERO BALANCE® Dermal Filler is injected into the skin in a simple, quick procedure using a fine gauge needle that can even be done over your lunch hour.


Is it safe?

BELOTERO BALANCE® Dermal Filler is FDA approved, and has undergone testing in a clinical study to prove its safety.¹


Are there any side effects?

Just like any injection, you may experience mild irritation, swelling itching, redness, bruising or tenderness at the injection site. These side effects typically resolve on their own. If any of these side effects persist, call your doctor immediately.


How long is the recovery time?

There is very little to no downtime associated with a BELOTERO BALANCE® Dermal Filler procedure. In fact, most patients return to their normal daily activities right after their visit. Every patient is unique, so be sure to discuss your plans with your doctor during your consultation.

¹Flynn, T. et al. 2011. Comparative Histology of Intradermal Implantation of Mono and Biphasic Hyaluronic Fillers, Dermatol Surg, 37 (5), 637-643
² BELOTERO BALANCE® Instructions for Use, June 2012

Radiesse®

Radiesse® dermal filler is a safe, next generation filler that does more than just fill in lines and wrinkles – it volumizes. In fact, Radiesse dermal filler is setting a new standard in facial fold and wrinkle correction. This treatment restores a natural, youthful look that lasts. In many patients, the results may last for a year or more. Numerous medical studies have shown that Radiesse dermal filler is a safe and effective treatment for filling and correcting smile lines, nasolabial folds, and wrinkles around the nose and mouth. Radiesse dermal filler stimulates the body to produce new collagen. This unique response provides immediate, visible improvement of folds and wrinkles, and provides long-lasting and beautiful results.

Before/After

*Individual results may varry

Radiesse® FAQs

What is Radiesse® Volumizing Filler?

Radiesse® Volumizing Filler is an injectable wrinkle filler that works by immediately restoring facial volume to smooth out the signs of aging. One injected, not only does it immediately add volume but over time, Radiesse® Volumizing Filler begins to stimulate the production of the body’s natural collagen for results that may last up to a year or more in many patients.


What is Radiesse® Volumizing Filler made from?

Radiesse® Volumizing Filler is made of tiny calcium-based microspheres suspended in a water-based gel. The calcium microspheres are similar to minerals found naturally in the body so allergy testing is not required. Over time, the body absorbs the microspheres and gel, leaving behind only natural collagen.


How does Radiesse® Volumizing Filler work?

Once injected, Radiesse® Volumizing Filler plumps the skin and replenishes volume lost over time for a more refreshed look. Over time, Radiesse® Volumizing Filler works to stimulate the body to produce collagen naturally. Ultimately the body absorbs the product and leaves behind the natural collagen for long-lasting results.²˒³


Where can Radiesse® Volumizing Filler be injected?

Radiesse® Volumizing Filler can be injected in the following locations*:

Smile lines: also called the nasolabial folds, are the lines that run from the corners of the nose to the corners of the mouth

Marionette lines: the lines that run downward from the corners of the mouth

Corners of the mouth: also called the oral commissure, if these are turned downward it can make you look like you are frowning

Pre-jowl: the area on either side of the chin, where skin can sag due to loss of facial volume

Chin wrinkles: horizontal lines that can form on your chin and distract from your smile

* Radiesse® Volumizing Filler is FDA-approved for correction of moderate to severe wrinkles and folds, such as nasolabial folds.


What makes Radiesse® Volumizing Filler different from other leading dermal fillers?

Radiesse® Volumizing Filler is the only dermal filler available composed of calcium-based microspheres, and is clinically proven to stimulate the natural production of collagen, for results that may last up to a year or more in many patients. ¹˒²˒³ Additionally, in clinical studies with leading hyaluronic acid injectable dermal fillers, results showed that Radiesse patients were significantly more satisfied with their results than patients treated with other leading wrinkle fillers.²˒⁴ In addition, 30% less Radiesse® Volumizing Filler may be needed for correction when compared to Perlane® injectable gel.


How is treatment with Radiesse® Volumizing Filler performed? Is it painful?

Radiesse® Volumizing Filler is injected under the skin in a safe and quick procedure that can be done over the lunch hour. Radiesse® Volumizing Filler is also FDA-approved to mix with lidocaine (an anesthetic), which means the procedure will be much more comfortable. In fact, in a clinical study, 90% of patients treated reported significant pain reduction when injected with Radiesse® Volumizing Filler mixed with lidocaine.


How soon will I see results with Radiesse® Volumizing Filler, and how long will it last?

Immediately upon injection, Radiesse® Volumizing Filler restores volume to smooth out the signs of aging. The natural-looking results may last up to a year or more in many patients. ²˒³


What are the side effects of treatment with Radiesse® Volumizing Filler?

As with any injection, patients may experience side effects such as mild irritation, swelling, itching, redness, bruising or tenderness at the injection site, which typically resolve on their own. If any of these side effects persist, contact your healthcare professional right away.


Is there anyone who should not use Radiesse® Volumizing Filler?

Radiesse® Volumizing Filler should not be used in patients with severe allergies manifested by a history of anaphylaxis, a history or presence of multiple severe allergies or patients with known hypersensitivity to any of the components.

¹Berlin A, Hussain M, Goldberg D. (2008) Calcium Hydroxylapatite Filler (Radiesse®) for Facial Rejuvenation: A Histologic and Immunohistochemical Analysis. Dermatologic Surgery. Volume 34, S64-S67.

²Moers-Carpi M Vogt S, et. Al (2007)A Multicenter, Randomized Trial Comparing Calcium Hydroxylapatite to Two Hyaluronic Acids for Treatment of Nasolabial Folds, Dermatologic Surgery. 33 (2S), 144s-151s.

³Bass LS< Smith S, Busso M, McClaren M. (2010) Calcium Hydroxylapatite (Radiesse®) for Treatment of Nasolabial Folds: Long-Term Safety and Efficacy Results.

⁴Moers-Carpi M, Tufet J. (2007) Calcium Hydroxylapatite versus Nonanimal Stabilized Hyaluronic Acid for the Correction of Nasolabial Folds: A 12-Month, Multicenter Prospective, Randomized, Controlled, Split-Face Trial, Dermatologic Surgery, 2008: 34:210-215.